FIGURE 8.

The PDZ motif is critical for the ability of δ-catenin to regulate spine architecture. a, schematic of constructs used. b, representative images of dendrites from neurons expressing vector, shRNA, or shRNA + the indicated constructs. c, quantitation of spine head width and d, spine length in neurons expressing vector, shRNA, or shRNA + indicated constructs (p values: *, <0.05; **, <0.005; ***, <0.0005, one-way ANOVA and Dunnett's multiple comparison test with single pooled variance; scale, 5 μm).