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. 2015 Mar 18;290(17):11177–11187. doi: 10.1074/jbc.M115.641514

FIGURE 1.

FIGURE 1.

Conditioned medium from C26 cancer cells activates p-Stat3 in C2C12 myotubes, a model of skeletal muscle. A, representative Western blots for p-Stat3 and Stat3 exposed to the conditioned medium of C26 for different times. B, representative Western blots for p-Stat3 or Stat3 with or without C188-9 in conditioned medium for 15 min. C, the average sizes of C2C12 myotubes following a 72-h incubation in C26-conditioned medium with or without C188-9. Error bars indicate means ± S.E. D, representative Western blots of caspase-3 and cleaved caspase-3 of C2C12 incubated in C26-conditioned medium. E, representative Western blots of pro-caspase-3 in C2C12 myotubes treated with C26-conditioned medium with or without C188-9. F, representative Western blots of C/EBPδ and myostatin in C2C12 myotubes treated with C26-conditioned medium with or without C188-9. CTRL, control.