Fig. 3.

Cellular cholesterol efflux by simple and ABCG1-facilitated diffusion to fmHDL and HDL₃. A: Cholesterol efflux from BHK-ABCG1 cells by simple diffusion (i.e., in the absence of mifepristone treatment to induce ABCG1 expression). B: To calculate ABCG1-facilitated cholesterol efflux, the average percent of unmediated efflux to each acceptor in (A) was subtracted from the corresponding individual cholesterol efflux values in cells expressing ABCG1 (i.e., treated with mifepristone). Values are the mean ± SEM (n = 9). ***P < 0.001; **P < 0.01; ns, not significant.