Table 1. Titanium dosage in organs and urine performed by ICP-OES.
| μg Ti/Organs | Control | 10 mn | 1h | 1 day | 7 days | 28 days | 56 days |
|---|---|---|---|---|---|---|---|
| Kidneys | 0.95 ± 0.34 | 1.34 ± 0.77 | 0.88 ±0.5 | 1.11± 0.26 | 0.87± 0.26 | 1.29± 0.19 | 1.21± 0.76 |
| Brain | 0.34±0.21 | 0.31±0.20 | 0.30±0.05 | 0.30±0.06 | 0.35± 0.09 | 0.37± 0.17 | 0.29± 0.15 |
| Spleen | 0.42± 0.3 | 16.1± 9.05* | 25.7±31.9* | 35,2± 18.1* | 31.7± 5.31* | 24.1± 0.31* | 13.8± 0.81* |
| Lungs | 0.2 ± 0.1 | 5.77±2.32* | 4.81±5.38 | 6.89±2.03* | 5.59± 1.01* | 2.01± 0.14* | 7.93± 2.36* |
| Liver | 0.03± 0.01 | 637±76* | 793±210* | 939±160* | 813±176* | 457±211* | 58± 14* |
| Blood | 0.12± 0.05 | 0.33± 0.11 | 0.15± 0.02 | 0.23±0.13 | 0.21± 0.05 | 0.09± 0.05 | N.D. |
| LN | 0.24± 0.14 | 0.23± 0.09 | 0.25± 0.13 | 0.16± 0.04 | 0.23± 0.12 | 0.25± 0.07 | N.D. |
| Testis | 0.32±0.19 | 0.35± 0.14 | 0.32± 0.06 | 0.21±0.06 | 0.28± 0.09 | 0.28± 0.08 | 0.24± 0.14 |
| Control | J1 | J3 | J6 | J27 | |||
| Urine | 0.12± 0.03 | 1.03± 0.71* | 0.14± 0.11 | 0.33± 0.28 | 0.61± 0.60 |
N.D. Not determined
Each value represents mean from 6 independent experiments ± SD. For each suspension, 3 measurements were performed.
(*) represent a statistical difference (p<0.05).