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. 2015 Apr 24;10(4):e0124266. doi: 10.1371/journal.pone.0124266

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© 2015 Zhu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — (A) Effects of pLenO-RFP-let-7c (Lv-let-7c) and pLenO-RFP (Lv-control, negative control) in the xenograft mouse model are shown. Data are shown as the mean ± S.D. The statistical difference was analyzed by the two-sample t test. (B) qRT-PCR assays of mature let-7c expression in tissues of the Lv-let-7c and Lv-control group. (C) Weight of tumors of mice in the Lv-let-7c and Lv-control groups. Data are shown as the mean ± S.D. The statistical difference was analyzed by the two-sample t test. (D) Photographs of tumors are presented. The three smallest tumors in the Lv-let-7c group are indicated by blue arrows.