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A: Crystal structures of TpbA (grey), DUSP23 (PDB ID: 2IMG, pale yellow), DUSP10 (PDB ID: 1ZZW, pale green), Cdc14B (PDB ID: 1OHE, light pink), DUSP5 (PDB ID: 2G6Z, pale cyan) and DUF442 (PDB ID: 3GXG, wheat). Functionally important loops are coloured as follows: PTP loop, blue; general acid loop, green; variable insert, yellow; α4-α5 loop, purple.
