Table 1. Comparison of BIM deletion polymorphism in women benign breast disease and two breast cancer cohorts with healthy volunteers among age groups.
| No. (%) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤35 years | 36–50 years | >50 years | Whole | |||||||||
| BIM polymorphism | wild | deleted | P | wild | deleted | P | wild | deleted | P | wild | deleted | P |
| Healthy (reference) | 42 (88) | 6 (13) | 140 (86) | 22 (14) | 125 (86) | 20 (14) | 307 (86) | 48 (14) | ||||
| Consecutive cohort | 37 (71) | 15 (29) | 0.045 | 254 (78) | 71 (22) | 0.029 | 267 (85) | 48 (15) | 0.640 | 558 (81) | 134 (19) | 0.018 |
| Metastatic cohort | 9 (60) | 6 (40) | 0.028* | 62 (78) | 18 (23) | 0.079 | 82 (87) | 12 (13) | 0.820 | 153 (81) | 36 (19) | 0.089 |
* two tailed Fisher’s exact test.