Table 2.
Association of Patient Characteristics with UTxB2 (pg/mg creatinine) in the absence of platelet-COX-1 activity.
| Characteristic | Category | Mean(SD) | Med(range) | P |
|---|---|---|---|---|
| Total | 325(423) | 255(69–2829) | – | |
| Gender | Male | 325(495) | 222(69–2829) | 0.159 |
| Female | 327(122) | 350(106–504) | ||
| Race | Cauc. | 335(499) | 255(69–2829) | 0.642 |
| Other | 306(200) | 277(83–739) | ||
| Smoking | Never | 246(168) | 244(69–692) | 0.041 |
| Current | 966(1248) | 426(184–2829) | 0.017* | |
| Former | 273(164) | 244(74–739) | ||
| Diabetes | Yes | 296(188) | 312(70–692) | 0.938 |
| No | 336(480) | 238(69–2829) | ||
| Hypertension | Yes | 278(166) | 261(70–739) | 0.899 |
| No | 535(937) | 194(69–2829) | ||
| Dyslipidemia | Yes | 265(176) | 244(69–739) | 0.084 |
| No | 641(968) | 321(144–2829) | ||
| History of MI, CABG, PCI | Yes | 277(165) | 247(74–692) | 0.975 |
| No | 367(560) | 255(69–2829) | ||
| History of stroke, PAD or CEA | Yes | 342(190) | 321(74–544) | 0.555 |
| No | 323(446) | 238(69–2829) | ||
| History of CHF | Yes | 317(229) | 315(74–739) | 0.896 |
| No | 331(465) | 249(69–2829) | ||
| No obstructive CADa | Yes | 536(931) | 249(70–2829) | 0.712 |
| No | 277(172) | 261(69–739) | ||
| Acute MI | Yes | 297(167) | 312(69–739) | 0.521 |
| No | 356(587) | 244(70–2829) | ||
| Statin use at enrollment | Yes | 243 (121) | 233 (83–447) | 0.652 |
| No | 354 (484) | 258 (69–2829) | ||
|
| ||||
| b1 | P | |||
|
| ||||
| Age | 0.0036 | 0.388 | ||
| BMI | 0.0033 | 0.675 | ||
| SBP | 0.0017 | 0.435 | ||
| DBP | −0.0017 | 0.641 | ||
| AAA | −0.032 | 0.211 | ||
*
P-value for current vs. former/never; Log 10 UTxB2 used for p-values.
MI = Myocardial infarction; CABG = Coronary artery bypass graft, PCI = Percutaneous coronary intervention; PAD = Peripheral artery disease; CEA = Carotid endarterectomy; CHF = Congestive heart failure; CAD = Coronary artery disease; BMI = Body mass index; SBP = Systolic blood pressure; DBP = Diastolic blood pressure; AAA = Arachidonic acid aggregometry.
Bold text notes those variables which have met statistical significance at the 0.05 levels.
a
No coronary stenosis >50%.