Table 1.
Overall characteristics of 1,277 eligible subjects from two African cohorts.
| Subjects from Kigali, Rwandaa | Subjects from Lusaka, Zambiaa | |||||
|---|---|---|---|---|---|---|
| Baseline characteristics | HESNs | SCs | SPs | HESNs | SCs | SPs |
| No. of subjects | 228 | 61 | 226 | 258 | 252 | 252 |
| Sex ratio (M/F) | 0.97 (112/116) | 1.03 (31/30) | 0.93 (109/117) | 1.12 (136/122) | 0.65 (99/153) | 0.84 (115/137) |
| Earliest enrollment date | Aug. 2002 | Jan. 2002 | Aug. 2002 | Mar. 1995 | Mar. 1995 | Mar. 1995 |
| Latest enrollment date | Mar. 2005 | Feb. 2011 | Jan. 2005 | Jan. 2006 | Jun. 2009 | Jan. 2006 |
| Age at enrollment: mean ± SD | 31.8 ± 7.3 | 30.7 ± 8.9 | 32.5 ± 7.4 | 32.2 ± 8.4 | 28.6 ± 7.5 | 31.8 ± 8.0 |
| Follow-up visitsa: median (IQR) | 16 (12–20) | 4 (3–9) | 14 (10–17) | 18 (10–28) | 8 (4–13) | 13 (6–22) |
| Follow-up time (months)b: median (IQR) | 48 (35–60) | 10 (6–23) | 48 (34–60) | 53 (27–81) | 18 (9–39) | 51 (27–75) |
| Genital ulcer/inflammation (GUI)c: no. (%) | 26 (11.4) | 19 (31.2) | 49 (21.7) | 43 (16.7) | 105 (41.7) | 81 (32.1) |
a
For this study, each cohort is divided into three subgroups. Abbreviations and the last eligible visit are defined in the text (see Methods).
b
P <0.001 between HESNs and SCs in each cohort.
c
As recorded in the last 12 months of follow-up before HIV-1 transmission or end of last visits.