. Author manuscript; available in PMC: 2015 Oct 1.

Published in final edited form as: Genes Immun. 2015 Jan 29;16(3):213–220. doi: 10.1038/gene.2014.84

Table 3.

Sensitivity analyses: alternative logistic regression models for 1,277 subjects (515 Rwandans and 762 Zambians).

	Baseline model: 478 seropositives vs. 799 seronegatives^b			Interim model: 678 seropositives vs. 599 seronegatives-^c
Factors^a in model	OR	95% CI	Adjusted P	OR	95% CI	Adjusted P
Age >40 years	1.18	0.84–1.68	0.343	0.85	0.61–1.20	0.363
Female sex	1.07	0.85–1.37	0.557	1.20	0.95–1.51	0.129
Country (Rwanda)	3.50	1.27–9.62	0.015	1.18	0.44–3.13	0.742
rs12407485-A	0.71	0.55–0.90	0.005^d	0.69	0.55–0.87	0.002^d

As defined in Table 1 and text. Odds ratio (OR) and confidence interval (CI) are further adjusted for genetic ancestry (MDS1-MDS4, see text). OR >1.0 is unfavorable (being seropositive).

At enrollment, only SPs (n = 478) are HIV-1 seropositive, while the other subjects (n = 799) are seronegative.

Up to two years of follow-up after enrollment, with 200 confirmed seroconversion events (as in Figure 3).

P ≥0.19 when corrected for 95 independent tests.