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. Author manuscript; available in PMC: 2015 Oct 23.
Published in final edited form as: Nature. 2015 Apr 8;520(7548):511–517. doi: 10.1038/nature14367

Extended Data Figure 2. Initial single-particle cryo-EM study of hTRPA1.

Extended Data Figure 2

a, Raw micrograph of MBP-hTRPA1 recorded using a scintillator-based CMOS camera. b, 2D class averages of MBP-hTRPA1 particles. c, Euler angle distribution of initial 3D reconstruction. d, FSC curve of final 3D reconstruction. e, Final 3D reconstruction of MBP-hTRPA1 at 28Å resolution. This 3D reconstruction was used as the initial model for subsequent cryo-EM studies of hTRPA1 using a direct electron detection camera.