Skip to main content
. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Hum Mutat. 2015 Apr 6;36(5):524–534. doi: 10.1002/humu.22770

Table 1.

Lists of most frequent, most harmful variations (gray columns, with degree of harmfulness > 50% and frequency > 0.5%) and most frequent, least harmful variations (with degree of harmfulness less than 20% and frequency > 0.5%)

Variation Frequency (%) Degree of Harmfulness Variation Frequency (%) Degree of Harmfulness
RC 2.52 0.52 VI 1.82 0.10
GR 2.39 0.59 IV 1.47 0.08
RW 2.18 0.53 TA 1.33 0.13
LP 2.06 0.63 VA 1.07 0.17
GD 1.27 0.57 LV 0.93 0.19
YC 1.13 0.59 SN 0.90 0.19
GE 1.04 0.53 KR 0.82 0.16
CY 0.96 0.67 ED 0.81 0.16
GV 0.95 0.61 DE 0.69 0.19
CR 0.93 0.63 SG 0.64 0.15
RP 0.74 0.63 AS 0.62 0.16
LR 0.65 0.60 RK 0.58 0.12
WR 0.56 0.56 EQ 0.58 0.18
FS 0.54 0.52 TS 0.55 0.10