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Pharmacokinetic parameters of USL255 200 mg once daily versus immediate-release topiramate 100 mg twice daily at steady state.
| USL255 | Immediate-release topiramate | |
|---|---|---|
| Area under curve (mg h/L) | 158 (32) | 153 (33) |
| Peak plasma concentration (mg/L) | 7.9 (1.5) | 8.4 (1.7) |
| Trough plasma concentration (mg/L) | 5.3 (1.2) | 5.0 (1.2) |
