Table 3.
Overview and comparison of data described in the main literature concerning ischaemic heart disease during pregnancy and this study
| Literature (women) | Ladner et al. [5] (N = 151) | Satoh et al. [17] (N = 62) | James et al. [4] (N = 859) | Roth et al. [6] (N = 103) | This study Overall (N = 146) |
This study Contemporary only (N = 57) |
|---|---|---|---|---|---|---|
| Years of inclusion | 1991–2000 | 1981–2001 | 2000–2002 | 1995–2005 | 1978–2012 | 2005–2012 |
| Mean age of women (years) | 31–35 | 33 | 33 | 33 | 33.2 | 33.5 |
| Most common timing of coronary event (N) | Post-partum (62) | Post-partum (28) | During pregnancy, not specified (626) | During pregnancy, not specified (46) | During pregnancy, third trimester (56) | During pregnancy, third trimester (25) |
| Most common location of AMI (N) | a | Including anterior wall (31) | Including anterior wall (215) | Including anterior wall (73) | Including anterior wall (80) | Including anterior wall (26) |
| Most common aetiology of IHD (N) | a | Coronary dissection (14) | a | Coronary stenosis (41) | Coronary dissection (46) | Thrombus/embolism (20) |
| Most common risk factor for IHD (N) | HTa | Smoking (9) | a | Smoking (46) | Smoking (40) | Smoking (17) |
| Maternal mortality (N) | 7.3 % (11) | 3.2 %a (2) | 5.1 % (44) | 11 % (11) | 8 % (11) | 6 % (3) |
| Most common (other) maternal cardiac complication (N) | a | Cardiogenic shock (5), VF/VT (5), HF (5) | a | HF (9) | VT (17) | VT (3) |
| Most common maternal obstetric complication (N) | PIH (24) | PPH (1) | PPHa | Pre-eclampsia (6) | PIH (46) | PIH (6) |
| Caesarean section rate (N) | a | b | a | 38 % (39) | 57 % (75) | 67 % (36) |
| Perinatal mortality (N) | a | a | a | 9 % (6) | 4 % (5) | 6 % (3) |
| Most common offspring complication (N) | Prematuritya | Threatened premature delivery (3) | a | a | Prematurity (55) | Prematurity (28) |
Offspring mortality is defined as offspring death from 20 weeks of gestation up to 7 days post-partum; prematurity is defined as birth at < 37 weeks of gestation
Missing data were excluded for analysis
aUnknown or not clearly reported data
bAt least seven women; incompletely documented
AMI acute myocardial infarction; HF heart failure; HT essential hypertension; IHD ischaemic heart disease; PIH pregnancy-induced hypertensive disorders, including pre-eclampsia, eclampsia and haemolysis, elevated liver enzymes and low platelets syndrome; PPH post-partum haemorrhage; VF ventricular fibrillation; VT ventricular tachycardia