Fig. 2.

Visual acuity in Isl2-EphA3 knock-in mice. a In the visual cliff test, WT, EphA3KI/+ and EphA3KI/KI mice spent significantly more time on the opaque side compared to the cliff side. The three groups of mice did not differ in terms of mean time (s) spent on the opaque side and cliff side during the 10 min session. b The latency to step down toward the opaque side was significantly lowered compared to the cliff side, but similar in all genotypes. c In the OKR test, the average contrast sensitivity (threshold contrast as  %, y axis) for spatial frequencies ranging from 0.064 to 0.272 cycles/degree (x axis) varies similarly in the three groups of mice. ***p < 0.0001