Fig. 3.

Locomotor activity and sensorimotor coordination in Isl2-EphA3 knock-in mice. a During the 3-h habituation phase, EphA3KI/KI and EphA3KI/+ mice did not differ from their WT littermates in terms of exploration of a new environment (expressed as mean horizontal activity per 15-min block). b EphA3KI/KI mice did not differ from their WT littermates in terms of mean time per trial to reach the platform over 4 trials of the beam test. In all three genotypes, this parameter decreased significantly over consecutive trials