Figure 8. Rat BMSCs encapsulated in 500 µm o-Alg beads embedded in PUR scaffolds survive transplantation for up to 7 days in a rat excisional wound model.
(A) SRY (sex determining region Y, Sox9) immunohistochemical staining revealed the presence of male donor rat BMSCs in wounds on female rats (black arrows) at day 7 (40× magnification). (B) qRT-PCR measurements of SRY expression show that cells survived for up to 7 days in implanted (Impl+BMSC) and injected (Inj+BMSC) scaffolds.