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(A) Transfection efficiency of Base and Guan copolymer polyplexes at N/P=15 to primary murine neural progenitor cells. Transfection efficiency was determined by delivering the luciferase plasmid and analyzing photon production from cell lysates. (B) Cytotoxicity of Base and Guan copolymer polyplexes at N/P=15 to primary murine neural progenitor cells as determined by protein content in cell lysate 48 hrs post transfection. Data shown as mean + SD.
