TABLE 1.
Baseline characteristics of participants with and without incident osteoporotic fracture in a case-cohort study of participants in the AGES-Reykjavik Study1
| With fracture | Without fracture | P | |
| Participants, n | 540 | 898 | |
| Women, n (%) | 350 (64.8) | 469 (52.2) | <0.001 |
| Age at study baseline,2 y | 78.5 ± 5.69 | 76.5 ± 5.48 | <0.001 |
| Age at fracture,3 y | 82.2 ± 6.02 | — | — |
| Education less than high school, n (%) | 157 (29.1) | 206 (22.9) | 0.005 |
| Current smoker, n (%) | 58 (11.2) | 103 (11.7) | 0.004 |
| Height,2 cm | 165 ± 9.20 | 168 ± 9.21 | <0.001 |
| Weight,2 kg | 72.1 ± 14.2 | 76.6 ± 13.9 | <0.001 |
| BMI,2 kg/m2 | 26.3 ± 4.17 | 26.3 ± 4.29 | <0.001 |
| Frequency of moderate-to-vigorous physical activity, n (%) | <0.001 | ||
| Never | 279 (56.0) | 378 (43.0) | |
| Rarely | 73 (14.7) | 156 (17.8) | |
| Occasionally | 30 (6.02) | 57 (6.48) | |
| Moderate | 7 (14.1) | 134 (15.2) | |
| High | 46 (9.24) | 154 (17.5) | |
| Prevalent diabetes, n (%) | 67 (12.4) | 111 (12.4) | 0.98 |
| Glucocorticoid medication, n (%) | 14 (2.82) | 22 (2.66) | 0.86 |
| Estrogen medication, n (%) | 23 (4.30) | 48 (5.35) | 0.45 |
| Osteoporosis medication,4 n (%) | 11 (2.06) | 19 (2.12) | 1.00 |
1
Differences between groups were tested by using 2-sided t tests for continuous variables and the chi-square test for categorical variables or Fisher's exact test for cells with frequency <5%. For the following variables, n varies because of missing data: smoking, n = 37; BMI, n = 9; height, n = 5; weight, n = 4; physical activity, n = 61; and glucocorticoid medication, n = 116. AGES-Reykjavik, Age, Gene/Environment Susceptibility Study.
2
Values are means ± SDs.
3
Values are medians ± SDs
4
Excludes estrogen use.