Table 2.
Sensitivity and Specificity of Phosphatidylethanol (PEth) for Past-Month Drinking
Drinking State | PEth Concentration* (ng/mL) | Sensitivity (95% confidence interval) | Specificity (95% confidence interval) |
---|---|---|---|
Any drinking | ≥8 | 79% (71–88) | 90% (81–98) |
Any drinking | ≥ 20 | 73% (65–80) | 96% (92–100) |
≥ 4 drinks/day | ≥ 20 | 97% (92–100) | 66% (59–73) |
≥ 4 drinks/day | ≥80 | 91% (82–100) | 77% (70–83) |
The PEth concentrations represent the original and improved limits of PEth quantitation and the concentration that maximized sensitivity+specificity for averaging at least 4 drinks daily as described in the text.