Table 4.

HA and NA changes between egg and MDCK cultured pairs of influenza A H3N2 viruses

Influenza A H3N2	Pass	NAI-HI b		HA (H3) c										NA (N2)
		CRBC	TRBC	131	138 d	158	167	186 e	190 d	193 e	194 d	229 e	246	148	221	312	399
Consensus a				A/T	A	K/E	T	S/G	D	S	L	R	N	T	K/E	I	D/E
A/Auckland/19/1996	Egg	-								R
	MDCK	+	-
A/Auckland/5/1996	Egg	-									I
	MDCK	+	-											I
A/Victoria/3/1999	Egg	-									I	I
	MDCK	+	+/−
A/Perth/201/2001	Egg	-				N					I	I
	MDCK	+	-	D			A
A/Christchurch/28/2003	Egg	-			S			D	V
	MDCK	+	+
A/Brisbane/3/2005	Egg	-						V					K
	MDCK	+	+														G
A/Brisbane/10/2007	Egg	-									P				K
	MDCK	+	+													T

^aConsensus sequence based on alignment of HAs and NAs in this study.

^bSee Tables 2 and 3. As no egg grown viruses were inhibited with CRBC they were not tested with TRBC.

^cH3 numbering [26].

^dH3 receptor binding site amino acids [26].

^eEgg adaptation amino acids of H3N2 viruses [24].