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. 2015 Feb 27;172(10):2469–2478. doi: 10.1111/bph.13073

Figure 2.

Figure 2

Acute effects of GDNF injection into the LC on neuropathic pain. (A) Mechanical allodynia and thermal hyperalgesia were assessed on the ipsilateral hind paw of CCI rats. A single dose of GDNF (1.5 μg) or saline was injected into the ipsilateral LC on day 7 after CCI. **P < 0.01; compared with saline treatment; unpaired t-test with Bonferroni correction; n = 4–6. (B) Noradrenaline content was assayed in the fifth lumbar dorsal spinal cord of CCI rats 24 h after GDNF or saline injection. *P < 0.05; compared with saline treatment; unpaired t-test; n = 3–6.