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. 2015 Mar 17;172(10):2507–2518. doi: 10.1111/bph.13074

Figure 3.

Figure 3

Effects of blocking μ receptors in the NTS of SHRs on μ-opioid receptor/α2A-adrenoceptor heterodimer formation and hypertension. (A) Representative BP recordings of an intra-NTS microinjection of the μ receptor antagonist CTAP in WKY rats and hypertensive SHRs. (B) The PLA images (red) and (C) summary results of μ receptor/α2A-adrenoceptor heterodimers in the NTS of WKY rats and hypertensive SHRs, 30 min after intra-NTS CTAP microinjection. Scale bar: 20 μm. Values shown are means ± SEM (n = 6). #P < 0.05, significantly different from WKY rats. *P < 0.05, significantly different from control SHRs.