. 2015 Mar 24;172(10):2634–2653. doi: 10.1111/bph.13087

Table 3.

Concentration-dependent enhancement by indacaterol of GRE-dependent transcription in BEAS-2B reporter cells

Glucocorticoid	Concentration (μM)	n	2× GRE BEAS-2B reporter activity (fold induction)		Fold enhancement by indacaterol^a	Indacaterol potency (p[A]₅₀ (M))
Glucocorticoid	Concentration (μM)	n	−Indacaterol	+Indacaterol	Fold enhancement by indacaterol^a	Indacaterol potency (p[A]₅₀ (M))
Fluticasone furoate	0.1	6	14.1 ± 0.58	51.7 ± 3.15	3.68 ± 0.19	9.18 ± 0.06
Dexamethasone	1	8	13.8 ± 0.71	45.1 ± 2.37	3.28 ± 0.13	9.12 ± 0.14
GSK 9027	3	5	8.50 ± 0.63	24.8 ± 1.03	2.94 ± 0.25	9.16 ± 0.04
Des-ciclesonide	0.1	6	9.85 ± 0.57	26.5 ± 1.53	2.72 ± 0.17	9.34 ± 0.18
GW 870086X	1	5	6.58 ± 0.18	17.4 ± 1.03	2.71 ± 0.14	9.46 ± 0.07
Mifepristone	1	4	1.10 ± 0.04	1.82 ± 0.15	1.61 ± 0.08	8.74 ± 0.13
Org 34517	1	8	1.04 ± 0.03	1.15 ± 0.03	1.11^b	8.67^b

Values calculated from the data shown in Figures 1G–L and 3B.

Maximum fold induction induced by GR ligand in the presence of indacaterol/maximum fold induction by GR ligand alone.

Values are the mean of eight experiments.