Table 3. Sub-arm analysis (n=47).
Arm, n (%) | PR, n (%) | SD, n (%) | PD, n (%) | ORR (CR+PR), n (%) | DCR (CR+PR+SD), n (%) |
---|---|---|---|---|---|
Arm A | |||||
Pathological examination | |||||
Adenocarcinoma (n=17) | 2 (11.8) | 7 (41.2) | 8 (47.1) | 2 (11.8) | 9 (52.9) |
Squamous carcinoma (n=7) | 2 (28.6) | 2 (28.6) | 3 (42.9) | 2 (28.6)△ | 4 (57.1)▽ |
Previous injection of paclitaxel | |||||
Yes (n=6) | 2 (33.3) | 1 (16.7) | 3 (50.0) | 2 (33.3) | 3 (50.0) |
No (n=18) | 2 (11.1) | 8 (44.4) | 8 (44.4) | 2 (11.1)# | 10 (55.6)※ |
Arm AP | |||||
Pathological examination | |||||
Adenocarcinoma (n=14) | 5 (35.7) | 3 (21.4) | 6 (42.9) | 5 (35.7) | 8 (57.1) |
Squamous carcinoma (n=9) | 1 (11.1) | 4 (44.4) | 4 (44.4) | 1 (11.1)□ | 5 (55.6)◆ |
Previous injection of paclitaxel | |||||
Yes (n=6) | 1 (16.7) | 2 (33.3) | 3 (50.0) | 1 (16.7) | 3 (50.0) |
No (n=17) | 5 (29.4) | 5 (29.4) | 7 (41.2) | 5 (29.4)◻ | 10 (58.8)■ |
A sub-arm: △, ORR in squamous carcinoma and non-squamous carcinoma by Fisher’s exact test, P=0.552, no significant difference between the two arms; ▽, DCR in squamous carcinoma and non-squamous carcinoma by Fisher’s exact test was P=1.000, no significant difference between the two arms; #, ORR with or without the application of paclitaxel by Fisher’s exact test was P=0.251, no significant difference between the two arms; ※, DCR with or without the application of paclitaxel by Fisher’s exact test was P=1.000, no significant difference between the two arms; AP sub-arm: □, ORR in squamous carcinoma and non-squamous carcinoma by Fisher’s exact test, P=0.34, no significant difference between the two arms; ◆, DCR in squamous carcinoma and non-squamous carcinoma by Fisher’s exact test was P=1.000, no significant difference between the two arms; ◻, ORR with or without the application of paclitaxel by Fisher’s exact test was P=1.000, no significant difference between the two arms; ■, DCR with or without the application of paclitaxel by Fisher’s exact test was P=1.000, no significant difference between the two arms. PR, partial response; SD, stable disease; PD, progressive disease; ORR, objective response rate; CR, complete response; DCR, disease control rate.