Table 3.
Risk of treatment failure in six study sites adjusted for age and sex
| Characteristic | PCR-corrected cure rate | Hazard ratio 1 (95% CI) | P value |
|---|---|---|---|
| Per protocol analysis | |||
| Age group(months) | |||
| 6 - 12 | 86.5% (32/37) | 1 | - |
| 13 - 24 | 91.1% (82/90) | 0.79 (0.25, 2.46) | 0.680 |
| 25 - 36 | 94.1% (48/51) | 0.46 (0.11, 1.95) | 0.289 |
| 37 - 59 | 93.7% (74/79) | 0.50 (0.14, 1.76) | 0.283 |
| Sex | |||
| Female | 90.5% (114/126) | 1 | |
| Male | 93.3% (125/134) | 0.71 (0.30, 1.72) | 0.457 |
| Study site | |||
| Karonga | 98.0% (49/50) | 1 | - |
| Kawale | 97.4% (38/39) | 1.25 (0.08, 20.28) | 0.873 |
| Machinga | 90.2% (37/41) | 4.76 (0.52, 43.34) | 0.166 |
| Mangochi | 97.4% (41/43) | 2.08 (0.19, 23.16) | 0.550 |
| Nkhotakota | 78.1% (32/41) | 10.60 (1.33, 83.94) | 0.025 |
| Rumphi | 91.3% (42/46) | 4.33 (0.48, 39.03) | 0.191 |
1Tested by Cox regression (95% Confidence Interval).