Table 9.
Fatty acid | Caucasian females | East Asian females | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
non (n = 161) | HC (n = 137) | p-value | non (n = 234) | HC (n = 43) | p-value | |||||
μg/ml | SD | μg/ml | SD | μg/ml | SD | μg/ml | SD | |||
18:2n6 | 616.5 | 138.1 | 671.1 | 139.0 | <0.01 | 664.0 | 140.6 | 698.0 | 128.1 | <0.05* |
18:3n3 | 14.0 | 7.3 | 16.6 | 6.3 | <0.01* | 15.3 | 6.1 | 17.8 | 7.7 | 0.05 |
20:4n6 | 115.9 | 34.1 | 140.7 | 36.6 | <0.01* | 112.4 | 30.4 | 123.1 | 31.6 | <0.01* |
20:5n3 | 12.0 | 8.7 | 11.3 | 7.5 | 0.42 | 12.6 | 9.6 | 14.0 | 11.3 | 0.45 |
22:6n3 | 27.7 | 12.1 | 35.4 | 11.7 | <0.01* | 34.8 | 11.5 | 37.5 | 14.7 | 0.23 |
[AA/LA] | 0.190 | 0.004 | 0.213 | 0.005 | <0.01* | 0.176 | 0.005 | 0.179 | 0.007 | 0.81 |
[DHA/ALA] | 2.3 | 1.1 | 2.4 | 1.0 | 0.42 | 2.5 | 1.1 | 2.4 | 1.1 | 0.38 |
[EPA/ALA] | 0.944 | 0.055 | 0.741 | 0.049 | <0.01* | 0.910 | 0.052 | 0.890 | 0.119 | 0.89 |
[DHA/EPA] | 2.8 | 1.2 | 3.8 | 1.6 | <0.01* | 3.6 | 1.5 | 4.1 | 2.6 | 0.06 |
Select fatty acids used as substrate and product of D5D and D6D desaturase indices. The * denotes p-values which are significant. P-values were determined using multiple linear regression models which were adjusted for BMI, age, dietary LA, ALA, EPA and DHA, % total energy from dietary fat and physical activity. Caucasian females: n = 298; East Asian Females: n = 277. Abbreviation: SD standard deviation.