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. Author manuscript; available in PMC: 2015 Apr 26.
Published in final edited form as: Acta Biomater. 2008 Oct 26;5(2):531–540. doi: 10.1016/j.actbio.2008.10.009

Table 2.

Strain dependence of specific proportions of GAGs retained within collagen gels seeded with leaflet or chordal cells.

Unconstrained Statically constrained Cyclic 2% Cyclic 5% Cyclic 10%
Leaflet % HA 12.6±0.7 11.3±1.4 24.7±8.7* 19.3±8.4* 15.0±2.7*
% 6-S 14.3±2.0* 11.8±2.5* 12.0±4.1* 11.0±1.2 y 13.1±1.4 y
% 4-S 73.1±1.3 77.0±4.0 63.4±6.6* 69.7±9.5* 71.9±1.7*x
Chordae % HA 12.4±0.7 11.6±1.5 4.9±4.0 4.0±1.6 2.6±0.5
% 6-S 18.4±1.1 18.4±1.1 18.8±1.8 13.7±1.3†‡y 14.0±1.7†‡ y
% 4-S 66.6±0.2 70.0±0.5φ 76.3±4.5 82.3±1.5 83.4±1.7‡x

Data are mean percentage ± standard deviation.

*

p<0.007 vs. chordae,

p<0.04 vs. 2%,

p<0.01 vs. unconstrained,

φ

p<0.03 vs. 10%.

When leaflet and chordal data were grouped together,

x

p<0.02 vs. 2%,

y

p<0.04 vs. unconstrained.