Table 4.
Strain dependence of specific proportions of GAGs secreted into culture medium surrounding collagen gels seeded with leaflet or chordal cells.
| Unconstrained | Statically constrained | Cyclic 2% | Cyclic 5% | Cyclic 10% | ||
|---|---|---|---|---|---|---|
| Leaflet | % HA | 56.3±8.1 | 51.5±13.5* | 48.2±5.6 | 49.5±4.1 | 60.1±5.6* |
| % 6-S | 11.1±1.4 | 12.4±2.6* | 10.4±1.2 | 8.9±0.3*x | 10.6±1.0 | |
| % 4-S | 27.0±6.4 | 32.9±9.3 | 38.7±3.2 | 39.4±3.9† | 29.8±5.3* | |
| Chordae | % HA | 49.8±15.1 | 36.2±4.6 | 46.8±4.8 | 40.9±5.8 | 43.1±10.8 |
| % 6-S | 14.7±0.6 | 19.2±0.3 | 12.9±3.3 | 12.9±4.9x | 12.0±3.1‡ | |
| % 4-S | 30.9±11.3 | 39.6±4.9 | 37.2±4.9 | 43.3±4.3 | 38.5±6.3 |
Data are mean ± standard deviation.
p<0.05 vs. chordae,
p<0.04 vs. statically constrained,
p<0.01 vs. unconstrained.
When leaflet and chordal data were grouped together,
p<0.05 vs. statically constrained.