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. Author manuscript; available in PMC: 2015 Apr 26.
Published in final edited form as: Acta Biomater. 2008 Oct 26;5(2):531–540. doi: 10.1016/j.actbio.2008.10.009

Table 4.

Strain dependence of specific proportions of GAGs secreted into culture medium surrounding collagen gels seeded with leaflet or chordal cells.

Unconstrained Statically constrained Cyclic 2% Cyclic 5% Cyclic 10%
Leaflet % HA 56.3±8.1 51.5±13.5* 48.2±5.6 49.5±4.1 60.1±5.6*
% 6-S 11.1±1.4 12.4±2.6* 10.4±1.2 8.9±0.3*x 10.6±1.0
% 4-S 27.0±6.4 32.9±9.3 38.7±3.2 39.4±3.9 29.8±5.3*
Chordae % HA 49.8±15.1 36.2±4.6 46.8±4.8 40.9±5.8 43.1±10.8
% 6-S 14.7±0.6 19.2±0.3 12.9±3.3 12.9±4.9x 12.0±3.1
% 4-S 30.9±11.3 39.6±4.9 37.2±4.9 43.3±4.3 38.5±6.3

Data are mean ± standard deviation.

*

p<0.05 vs. chordae,

p<0.04 vs. statically constrained,

p<0.01 vs. unconstrained.

When leaflet and chordal data were grouped together,

x

p<0.05 vs. statically constrained.