Table 2.
Dietary and Serum Choline-Related Metabolites among Controls and HIV-Infected Subjects
Control Subjects (n=67) | HIV-Infected Subjects (n=155) | P-value | |
---|---|---|---|
Dietary Intake | |||
Betaine, mg | 155.9 (90.3–208.9) | 128.9 (94.2–182.3) | 0.43 |
Choline, mg | 349.2 (251.5–464.8) | 330.7 (218.9–429.4) | 0.60 |
Serum Metabolites | |||
Betaine, μmol/L | 6.1 (4.7–7.7) | 5.8 (5.1–7.0) | 0.32 |
L-Carnitine, μmol/L | 5.9 (4.9–6.7) | 5.8 (4.5–6.9) | 0.58 |
Choline, μmol/L | 2.0 (1.8–2.2) | 1.9 (1.7–2.3) | 0.88 |
TMA, μmol/L | 0.3 (0.3–0.4) | 0.3 (0.3–1.5) | 0.50 |
TMAO, μmol/L | 0.7 (0.5–1.0) | 0.7 (0.5–1.1) | 0.79 |
Data reported as median (interquartile range). Abbreviations: TMA, trimethylamine; TMAO, trimethylamine-N-oxide.
Food record data were available for 36 control subjects and 100 HIV-infected subjects.