Skip to main content
. Author manuscript; available in PMC: 2016 Feb 20.
Published in final edited form as: AIDS. 2015 Feb 20;29(4):443–452. doi: 10.1097/QAD.0000000000000565

Table 4.

Table 4a. Univariate Associations with Choline Related Metabolites among HIV-Infected Subjects
Parameter Log Serum Betaine Log Serum L-Carnitine Log Serum Choline Log Serum TMA Log Serum TMAO
r P-value r P-value r P-value r P-value r P-value
Coronary Plaque Characteristics
Log Calcium Score −0.02 0.83 −0.006 0.94 0.10 0.22 0.22 0.006 0.06 0.47
Total Plaque Segments, # −0.001 0.99 −0.07 0.43 0.03 0.71 0.20 0.02 0.007 0.93
Noncalcified Plaque Segments, # 0.03 0.76 −0.13 0.13 0.02 0.82 0.11 0.18 0.007 0.93
Calcified Plaque Segments, # −0.19 0.03 0.10 0.23 −0.03 0.70 0.18 0.03 0.02 0.85
Total Calcium Volume of Plaque, mm3 −0.07 0.42 0.07 0.39 0.09 0.26 0.19 0.02 0.04 0.67
Total Calcium Mass of Plaque, mg −0.07 0.42 0.08 0.38 0.14 0.10 0.22 0.009 0.04 0.66
Inflammatory Indices
Log CRP, mg/dL 0.10 0.22 0.12 0.15 −0.14 0.08 0.11 0.18 0.06 0.47
Log hsIL-6, pg/mL 0.05 0.58 −0.14 0.11 0.006 0.94 −0.10 0.25 0.15 0.08
Log LPS, ng/mL 0.05 0.59 0.02 0.81 0.03 0.75 0.19 0.03 0.14 0.12
Table 4b. Univariate Associations with Choline Related Metabolites among Control Subjects
Parameter Log Serum Betaine Log Serum L-Carnitine Log Serum Choline Log Serum TMA Log Serum TMAO
r P-value r P-value r P-value r P-value r P-value
Coronary Plaque Characteristics
Log Calcium Score 0.02 0.86 0.08 0.52 −0.08 0.54 0.09 0.47 0.16 0.21
Total Plaque Segments, # 0.02 0.87 0.14 0.27 −0.05 0.72 0.14 0.29 0.02 0.90
Noncalcified Plaque Segments, # −0.03 0.80 0.18 0.17 −0.07 0.61 0.19 0.15 −0.14 0.27
Calcified Plaque Segments, # 0.06 0.65 0.07 0.58 0.06 0.63 −0.17 0.17 0.18 0.15
Total Calcium Volume of Plaque, mm3 0.22 0.08 0.24 0.06 −0.06 0.64 0.0003 1.00 0.12 0.34
Total Calcium Mass of Plaque, mg 0.21 0.09 0.24 0.06 −0.07 0.61 −0.02 0.89 0.13 0.29
Inflammatory Indices
Log CRP, mg/dL −0.0002 1.00 0.14 0.25 −0.10 0.44 0.16 0.20 −0.03 0.80
Log hsIL-6, pg/mL −0.21 0.13 −0.10 0.48 −0.05 0.71 0.04 0.79 0.09 0.54
Log LPS, ng/mL 0.15 0.28 0.15 0.28 0.07 0.64 −0.01 0.92 −0.08 0.56

r represents Pearson’s correlation coefficient.

Abbreviations: TMA, trimethylamine; TMAO, trimethylamine-N-oxide; CRP, C-reactive protein; hsIL-6, high sensitivity interleukin-6; LPS, lipopolysaccharide.

HHS Vulnerability Disclosure