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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Curr Top Med Chem. 2015;15(12):1138–1152. doi: 10.2174/1568026615666150413153400

Fig. (3).

Fig. (3)

(A) The structure and application of 111In-labeled, EGFR aptamer-conjugated HAuNS (EGFR-Apt-HAuNS) for SPECT/CT imaging in EGFR-positive OSC-19 xenografts. EGFR-Apt-HAuNS demonstrated faster penetration into OSC-19 tumors along with consistent accumulation when compared to EGFR-antibody (C225) conjugated HAuNS. Adapted with permission from reference [77]. (B) The use of 64Cu-labeled, AS1411-conjugated silica nanoparticles (NC20-AS1411) for PET imaging of 4T1 tumor-drained lymph nodes. 64Cu-labeled, unconjugated nanoparticles (NC20-ctrl) showed significantly lower uptake in these lymph nodes. Adapted with permission from reference [83].