Table 1.
Characteristics of Dark-Adapted ERG and Whole-Cell Responses in WT and RGS9-ox Mice
| A-wavemax (µV) |
B-wavemax (µV) |
Rmax (pA) |
Rmax (mV) |
Series Resistance (MΩ) |
Resting Potential (mV) |
Latency (ms) |
||
|---|---|---|---|---|---|---|---|---|
| DBCR | −84.6 ± 17.5 (21) | 22.4 ± 2.5 (9) | 191.5 ± 36.3 (21) | −32.2 ± 3.4 (9) | 64.0 ± 3.9 (21) | |||
| Wild-Type | −390 ± 36.5 | 608 ± 64.3 | HBC | 76.4 ± 15.5 (7) | −21.9 ± 3.3 (6) | 288.0 ± 115.9 (5) | −34.2 ± 0.9 (6) | 48.4 ± 4.7 (7) |
| HC | 255 ± 52.2 (3) | −19.0 ± 1.4 (3) | 56.8 ± 3.2 (2) | −41.5 ± 3.3 (3) | 42.5 ± 1.6 (3) | |||
| DBCR | −66.5 ± 11.1 (7) | 26.7 ± 2.7 (5) | 129.9 ± 42.7 (7) | −34.9 ± 4.0 (5) | 58.9 ± 3.1 (7) | |||
| RGS9-ox | −438 ± 36.0 | 702 ± 51.2 | HBC | 87.7 ± 31.9 (7) | −13.2 ± 1.7 (4) | 367.6 ± 97.6 (5) | −37.0 ± 4.7 (5) | 42.8 ± 3.5 (3) |
| HC | 346 ± 84.3 (3) | −19.4 ± 2.3 (3) | 91.7 ± 31.9 (3) | −35.8 ± 2.4 (3) | 44.7 ± 1.7 (3) |
Rmax, maximal response amplitude; DBCR, rod bipolar cell; HBC, hyperpolarizing bipolar cell; HC, horizontal cell