Table 3.
Medications and interventions (stroke/TIA vs no stroke/TIA)
| Variable | Before admission |
On discharge |
||||
|---|---|---|---|---|---|---|
| No stroke/TIA N=4601 (91.9%) | Stroke/TIA N=404 (8.1%) | p Value | No stroke/TIA N=4601 (91.9%) | Stroke/TIA N=404 (8.1%) | p Value | |
| Digoxin | 758 (16.5) | 92 (22.8) | 0.001 | 1112 (24.2) | 95 (23.5) | 0.77 |
| Oral nitrates | 1151 (25) | 154 (38.1) | 0.001 | 1636 (35.6) | 186 (46) | 0.001 |
| Hydralazine | 187 (4.1) | 34 (8.4) | 0.001 | 299 (6.5) | 54 (13.4 | 0.001 |
| Aspirin | 2781 (60.4) | 308 (76.2) | 0.001 | 3538 (76.9) | 313 (77.5) | 0.80 |
| Clopidogrel | 849 (18.5) | 117 (29) | 0.001 | 1631 (35.5) | 167 (41.3) | 0.02 |
| Oral anticoagulants (%) | 537 (11.7) | 81 (20) | 0.001 | 806 (17.5) | 91 (22.5) | 0.01 |
| Statin | 2269 (49.3) | 286 (70.8) | 0.001 | 311 (67.7) | 319 (79) | 0.001 |
| Allopurinol | 121 (2.6) | 14 (3.5) | 0.32 | 219 (4.8) | 20 (5) | 0.86 |
| Ivabradine (%) | 107 (2.3) | 8 (2.0) | 0.66 | 227 (4.9) | 17 (4.2) | 0.52 |
| Antiarrhythmic (%) | 116 (2.5) | 10 (2.5) | 0.96 | 208 (4.5) | 15 (3.7) | 0.45 |
| Antidepressants (%) | 57 (1.2) | 9 (2.2) | 0.10 | 82 (1.8) | 10 (2.5) | 0.32 |
| BB | ||||||
| Carvedilol | 992 (49.6) | 105 (50.2) | 0.87 | 1600 (51.6) | 140 (53.8) | 0.48 |
| Metoprolol | 197 (9.9) | 26 (12.4) | 0.24 | 295 (9.5) | 32 (12.3) | 0.14 |
| Bisoprolol | 648 (32.4) | 59 (28.2) | 0.22 | 1151 (37.1) | 80 (30.8) | 0.04 |
| ACE inhibitors | 1968 (42.8) | 164 (40.6) | 0.40 | 2694 (58.6) | 188 (46.5) | 0.001 |
| ARBs | 563 (12.2) | 84 (20.8) | 0.001 | 725 (15.8) | 77 (19.1) | 0.08 |
| Aldosterone antagonists | 778 (16.9) | 62 (15.3) | 0.42 | 1921 (41.8) | 135 (33.4) | 0.001 |
| Cardiac procedures | ||||||
| PCI | 484 (10.5) | 55 (13.6) | 0.05 | 2861 (6.2) | 13 (3.2) | 0.02 |
| CABG | 322 (7) | 44 (10.9) | 0.004 | 65 (1.4) | 4 (1.0) | 0.49 |
| Device therapy (yes) (%) | ||||||
| CRT-P | 4 (0.1) | 1 (0.2) | 2 (0) | 0 (0) | ||
| CRT-D | 52 (1.1) | 4 (1.0) | 26 (0.6) | 3 (0.7) | ||
| ICD | 80 (1.7) | 12 (3) | 0.37 | 45 (1.0) | 8 (2.0) | 0.10 |
| Valve repair/replacement (yes) (%) | 148 (3.2) | 19 (4.7) | 0.11 | 88 (1.9) | 6 (1.5) | 0.54 |
ARBs, angiotensin receptors blockers; BB, B blockers; CABG, coronary artery bypass grafting; CRT, cardiac resynchronization therapy; ICD, International Classification of Diseases; PCI, percutaneous coronary intervention; TIA, transient ischaemic attack.