Table 8.
Study name (reference) | Study period | Patient (n) | Mean age (years) | Female sex (%) | Strokes (%) | F/U* (days) |
---|---|---|---|---|---|---|
Granger et al26 North America Europe |
CHARM-Alternative trial 1999–2001 | 2028 | 66.5 | 31.9 | 3.8 | 1011 |
Mathew et al27 North America |
DIG trial 1991–1993 | 7788 | 63.9 | 24.7 | 4.2 | 1110 |
Pfeffer et al28 North America Europe |
CHARM-Overall programme 1999–2001 | 7599 | 66 | 31.6 | 1.4 | 1131 |
Dries et al29 North America |
SOLVD trial 1986–1989 | 6378 | 60 | 4.4 | 3.5 | 1197 |
McMurray et al30 26 countries worldwide |
CHARM-Added trial 1999 | 2548 | 64 | 21.3 | 3.4 | 1230 |
Remme et al31 Europe | COMET trial 1996–1999 | 3029 | 62 | 0.2 | 4.7 | 1740 |
Khafaji et al current study Middle East |
Gulf CARE 2012–2013 |
5005 | 66.5 | 40.8 | 8.1 | 360 |
*Included studies in the follow-up period. Gulf CARE, Gulf aCute heArt failuRe rEgistry.