Table 2.
Study/year of publication | Characteristics of PAD Population | Total Sample Size/Prevalence of PAD | Mean Age in Years (standard deviation)* | Percent Female (%) | Prevalence of Claudication in PAD participants | Prevalence of Asymptomatic PAD | Prevalence of Atypical Exertional Leg Symptoms |
---|---|---|---|---|---|---|---|
| |||||||
Community Dwelling Populations | |||||||
Lipid Research Clinics (1985) (29) | Community dwelling men and women in Southern California. | N=575 total/N=65 (11%) with PAD | 66 Range 38–82 |
59% | N=6 (9.2%) | Not reported. | Not reported. |
Cardiovascular Health Study (1993) (32) | Men and women age 65 and older from four United States Communities. | N=5,084 total/N=629 (12.4%) with ABI < 0.90 | 71.7 for those with ABI 0.90 to 1.50; 75.5 for those with ABI < 0.80. | :ABI < 0.80: 54.1% ABI 0.90 to 1.50: 60% |
2.0% overall | Not reported. | Not reported. |
Women’s Health and Aging Study (2000) (34) | Community dwelling women age 65 and older with disability and without leg pain. | N=933 N=328 (35%) with ABI < 0.90 |
PAD: 77.4 (7.3); Non-PAD: 75.5 (6.9) | 100% | Not reported. | N=198 (60.3%) | Not reported. |
Cardiovascular Health Study (2001) (33) | Men and women age 65 and older from four U.S. Communities. | N=5,888 overall N=723 with ABI < 0.90 (12%) |
Range from 72.7 (5.5) in people without leg pain to 74.9 (5.8) in those with intermittent claudication. | 54% | N= 62 (8.5%) | N=427 (59%) | N=234 (32%) |
| |||||||
Primary Care Medical Practices
| |||||||
General Medicine Study (1999) (35) | Patients age 55 and older in a general medical practice with no prior history of PAD. | N=174 N=26 with PAD (14.9%) |
PAD-69 (6.5) Non-PAD-68 (7.2) |
PAD-31% Non-PAD-65%) |
N=1 (3.8%) | N=14 (43.8%) | N=2 (7.7%) |
PARTNERS Study (2001) (36) | Primary care patients who were a) age 70 and older or b) age 50 to 69 with history of smoking or diabetes. | N=6,979 overall N=1,865 (27%) with ABI < 0.901 |
68.9 (10) among those without PAD. Mean age of PAD ranged from 70.8 (10.1) to 72.3 (9.1). |
52% overall | N=178 (9.5%) | N=572 (30.6%) | N=934 (50.1%) |
Texas Primary Care Practices (37) | Patients age 50 and older in a Veterans Administration and two primary care practices in Houston. | N=403 total sample N=67 with PAD |
Non-PAD: 63.5 (7.3). PAD: 65.3 (7.0) |
Non-PAD: 53% PAD: 49% |
N=5 (8%) | N=31 (47%) | N=30 (45%) |
Get ABI Study (2009) (31) | Patients age 65 and older in primary care medical practices in Germany. | N=6,880 total sample size N=1,429 (21%) with PAD |
Non-PAD: 72.2 + 5.1; PAD: 73.9 (5.6) | 58% | N=593 (41.5%) had any symptoms or had history of peripheral revascularization or amputation. | N=836 (58.5%) | Not reported. |
| |||||||
Non-invasive vascular laboratory
| |||||||
WALCS Chicago cohort (2001) (18) | Consecutive patients with PAD in a non-invasive vascular laboratory. | 460 PAD participants | 71.9 (8.4) | 41% | N=150 (32%) | N=91 (20%) | N=219 (47.6%) |
Standard deviation provided when available.