Table 2.
Treatment-related toxicity (grade ≥3) occurring in ≥5% of patients in one cycle or more of treatment
| Toxicity | Worst grade
reported, n (%) |
||
|---|---|---|---|
| 3 | 4 | 3 or 4 | |
| Overall worst grade per patient (any toxicity) | 18 (28.6) | 36 (57.1) | 54 (85.7) |
| Anaemia | 15 (23.8) | 1 (1.6) | 16 (25.4) |
| Leukopenia | 32 (50.8) | 8 (12.7) | 40 (63.5) |
| Neutropenia | 16 (25.4) | 31 (49.2) | 47 (74.6) |
| Thrombocytopenia | 21 (33.3) | 12 (19.0) | 33 (52.3) |
| Neutropenic fever or sepsis | 4 (6.3) | 3 (4.8) | 7 (11.1) |
| Combined GI toxicity (nausea, vomiting, or diarrhoea) | 7 (11.1) | 0 (0.0) | 7 (11.1) |
| Fatigue | 5 (7.9) | 0 (0.0) | 5 (7.9) |
GI = gastrointestinal.