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. Author manuscript; available in PMC: 2015 Apr 27.
Published in final edited form as: Nanotechnology. 2015 Feb 3;26(8):084002. doi: 10.1088/0957-4484/26/8/084002

Figure 1.

Figure 1

DNA immobilized within the αHL nanopore. A) Cartoon representation of a homopolymeric DNA oligonucleotide immobilized inside an αHL pore (grey) through the use of a 3′ biotin-TEG (yellow)-streptavidin (red)complex. The green, red and blue boxes represent R1, R2 and R3 recognition sites, respectively. B) The sequences of the oligonucleotides with single nucleobase substitutions at position 9 (green) and 14 (red) that were used to probe R1 and R2, respectively. The recognition site R3 is shown as a blue line.