Table 1.
Demographic Characteristics and Neurocognitive Performance by Diagnosis
| Controls (n=62) | Patients (n=53) | ||||
|---|---|---|---|---|---|
|
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| Percentage | Proportion | Percentage | Proportion | p-value | |
|
|
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| Gender (% Female) | 51.6 | 32F, 30M | 35.8 | 19F, 34M | 0.09 |
|
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| Mean (SD) | Range | Mean (SD) | Range | p-value | |
|
|
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| Age (years) | 36.1 (8.6) | 25–55 | 38.7 (9.8) | 25–55 | 0.14 |
| Education (years) | 14.9 (2.4) | 10–20 | 13.3 (2.6) | 6–20 | <0.001 |
| Parental Education (years) | 13.9 (3.1) | 6.5–20 | 13.4 (3.0) | 6–19.5 | 0.46 |
| Handedness (% Right) | 88.7% | 81.1% | - | 0.38 | |
| SANS Global Average | - | - | 1.4 (0.9) | 0–3.3 | - |
| SAPS Global Average | - | - | 1.4 (1.0) | 0–3.5 | - |
| Comorbid Diagnoses‡ | |||||
| SZ only | - | - | 22 | - | - |
| SZ + 1 | - | - | 18 | - | - |
| SZ + 2 | - | - | 12 | - | - |
| SZ + 3 | - | - | 1 | - | - |
| Age of Onset | - | - | 22.0 (6.4) | 9–37 | |
| Medication (Atypical/Typical) | - | - | 27/7 | - | - |
| Medication (CPZE)* | - | - | 428.4 (439.4) | - | - |
| GNP Accuracy (z-score) | 0.0 (0.6) | −2.0–1.3 | −0.6 (0.9) | −2.9–0.6 | - |
| GNP Speed (z-score) | 0.0 (0.6) | −2.0–0.9 | −0.9 (1.1) | −3.2–0.9 | - |
‡
Comorbid diagnoses included: Mood disorders, Substance Dependence and Substance Use.
*
Sixteen patients were receiving mood stabilizers, but not antipsychotics ; six patients reported no antipsychotic medication; antipsychotic dosage was unknown for two patients.