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. 2015 Feb 12;1(1):e1400234. doi: 10.1126/sciadv.1400234

Fig. 1. CENP-A and CENP-C enrichment decreases with α-satellite divergence in pericentric heterochromatin.

Fig. 1

Log-ratio CENP-A, CENP-C, and H3 enrichment profiles spanning the 40-kb most proximal annotated segment of chromosome arm Xp, which spans the DXZ1 α-satellite HOR gradient (3). Dense CENP-A and CENP-C enrichment diminishes with distance from the centromere-proximal edge, and depletion of H3 diminishes ~20 kb from the edge. Diverged α-satellite occupies the Xp arm punctuated by LINE-1 and other elements where centromere protein enrichment is low.