Table 4: Effect of Escitalopram on the histopathological changes in the brain striatum in 3-NP treated rats.

Groups	Remarks
NAD: No abnormality detected; +: Mild; ++: Moderate; +++: Severe.
Control	NAD. No evidence of degeneration
3-NP	Moderate to severe neurofibrillary degeneration in striatum and hippocampus region. (+++)
E-10 + 3-NP	Mild-Moderate foci of degeneration. (++)
E-20 + 3-NP	Patchy areas of degeneration are evident in the striatum and hippocampus region. (+)
E-20	NAD. No foci of degeneration.