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. 2015 Apr 21;7(1):48. doi: 10.1186/s13148-015-0081-5

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© Rezwan et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The performance of three t-tests (one-sample, Weisberg and Crawford-Howell t-tests) around the PLAGL1 region in TND-MLMD 1. The x-axis denotes the genomic location of PLAGL1 on chromosome 6. The y-axis represents the estimated percentage of the control population that would be expected to obtain lower score than the case (point estimate), which is calculated according to the one-sample (OS, red crossed line), Weisberg (WB, green line with green square markers) and Crawford-Howell (CH, blue line) methods. The blue shade represents 95% confidence interval of the point estimates from the noncentrality parameter from a noncentral t-distribution.