Table 1.

Screening protocol for transmissible diseases for potential donors to an FMT programme^a

Body fluid	Assays
Blood	Hepatitis A serology. Hepatitis B serology and hepatitis B DNA. Hepatitis C serology and hepatitis C RNA. HIV-1 and -2 and HTLV-1 and -2 serology. Syphilis serology. Cytomegalovirus and Epstein-Barr Virus serology. Entamoeba histolytica serology. Strongyloides stercoralis serology.
Stool	Microscopy, culture and sensitivity for enteric bacteria (at least three samples over three separate days). Analysis for ova, cysts and parasites (at least three samples over three separate days). Acid-fast staining for Cyclospora, Isospora and Cryptosporidium C. difficile toxin and PCR Analysis for Rotavirus and Adenovirus. Helicobacter pylori faecal antigen.

^aThis is the screening protocol currently used in the programme at Imperial College London; assays are repeated 6 monthly. In addition, donors complete detailed questionnaires regarding their medical, family and medication history when being considered as donors, and questionnaires regarding recent symptoms suggestive of GI disease or infection (as well as recent travel) when donating stool for processing into FMT.