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. 2015 Apr 21;6:6847. doi: 10.1038/ncomms7847

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(a) Classification procedure on example interaction profiles belonging to the ‘X inhibits Y' and ‘Y restores X' interaction modes. The red line corresponds to the height of X+Y if the integration of the stimuli was additive. (b) Table showing the classification of the 82 interaction profiles in 10 groups called interaction modes. Each interaction mode contains a subset of interaction profiles that share a biological interpretation and satisfy common mathematical rules. The number of interaction profiles contained in each mode is shown as well as one representative interaction profile. Neg, negative; Pos, positive.