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. 2015 Apr 17;6:6861. doi: 10.1038/ncomms7861

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Schematic representation showing the features of the energy landscape of src SH3 on three different reaction coordinates. (a) the extension along the unzipping geometry, (b) the extension along the shearing geometry and (c) the solvent accessible surface area of src SH3. Bold lines represent the energy landscape in the absence of force and denaturant and dotted lines show the effect of force (a,b) or urea (c) on the energy landscape. Pathways S1 and S2 are not shown for the unzipping geometry (a) because we were unable to detect these pathways under unzipping forces.