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. Author manuscript; available in PMC: 2015 Apr 27.
Published in final edited form as: Psychiatry Res. 2011 Sep 29;194(2):130–140. doi: 10.1016/j.pscychresns.2011.07.002

Table 4.

Right anterior insula seed correlated activity in brain regions.a

Brain region Hemisphere MNI coordinates Cluster size Z-score p-value
X Y Z
S>O+Y
Frontal region
  Inferior frontal (46) Left −38 38 6 90 3.41 <0.001
  Middle frontal (10) Left −36 40 6 90 2.89 0.004
  Inferior frontal (45/44) Left −42 20 10 83 2.93 0.003
Parietal region
  Precuneus (31) Right 30 −78 22 287 3.31 0.001
  Cuneus (18) Right 26 −82 28 287 3.14 0.002
Temporal region
  Middle temporal (37) Left −46 −62 2 251 3.16 0.002
  Superior temporal (42/41) Left −62 −22 10 107 4.21 <0.001
  Superior temporal (22) Left −64 −32 12 107 2.52 0.012
  Superior temporal (41) Right 34 −32 12 91 2.78 0.006
Occipital region
  Middle occipital (19) Right 32 −78 22 287 3.59 <0.001
  Middle occipital (18) Left −24 −88 24 260 4.03 <0.001
  Medial occipital/fusiform (19/37) Left −30 −52 −2 251 4.41 <0.001
Paralimbic/subcortical
  Insula (13) Left −36 24 0 90 2.46 0.014
  Caudate Right 26 −32 14 91 2.36 0.018
  Thalamus Right 26 −28 12 91 2.77 0.006
  Putamen Left −26 2 2 157 3.3 0.001
  Claustrum Left −28 16 4 157 2.79 0.005
  Insula (13) Left −42 16 10 83 3.44 <0.001
M+F>O+Y
Frontal region
  Inferior frontal (13/47) Left −32 16 14 207 3.77 <0.001
  Dorsolateral frontal (6) Right 38 −12 36 146 3.12 0.002
Cingulate region
  Anterior cingulate (24) Left −4 30 −10 185 3.22 0.001
  Anterior cingulate (24) Right 2 22 −8 185 3.18 0.001
Parietal region
  Inferior parietal (40) Left −60 −22 14 225 2.92 0.004
  Inferior parietal (40) Right 32 −30 40 146 3.53 <0.001
  Superior parietal (3) Left −30 −26 42 99 3.28 0.001
  Inferior parietal (40) Left −42 −30 34 99 2.74 0.006
Temporal region
  Transverse temporal (41) Left −58 −22 12 225 4.03 <0.001
  Superior temporal (42) Left −54 −28 18 225 2.87 0.004
Paralimbic/subcortical
  Insula (13) Left −48 −20 14 225 2.49 0.013
  Insula (13) Left −32 16 10 207 3.55 <0.001
  Claustrum Left −28 12 10 207 3.23 0.001
  Putamen Left −26 10 2 207 2.9 0.004
  Caudate Right 6 18 −6 185 2.83 0.005
  Caudate Left −6 16 −10 185 2.52 0.012
S>M+F
  Middle occipital (19) Left −40 −70 12 165 3.73 <0.001
  Middle temporal (37) Left −42 −68 12 165 3.1 0.002
M+F>S
  Medial frontal (10) Left −12 56 12 173 3.33 0.001
  Superior frontal (10) Left −18 62 12 173 2.6 0.009

BA = Brodmann Area.

a

Used a statistical threshold of p = 0.01 (uncorrected) with minimal cluster size of 10 voxels and then the resulting clusters were corrected for whole brain multiple comparisons. The brain regions listed were significant at p = 0.05 corrected for multiple comparison at cluster level based on Monte Carlo simulations performed by AlphaSim.