Table 2.
Values of selected biomarkers in nonobese and obese children
| n | Nonobese (n = 94) | Obese (n = 29) | P valuea | P valueb | |
|---|---|---|---|---|---|
| IMCL (% water peak) | 99 | 0.44 ± 0.21 | 0.74 ± 0.39 | <0.0001 | 0.47 |
| IHL (% water peak) | 92 | 0.54 ± 0.42 | 1.49 ± 1.13 | <0.0001 | <0.01 |
| VAT (cm2) | 83 | 10.62 ± 5.44 | 20.16 ± 8.01 | <0.0001 | 0.18 |
| Insulin sensitivity (mμ/l)−1•min−1 | 40 | 13.43 ± 8.18 | 5.9 ± 5.98 | 0.01 | 0.19 |
| Insulin resistance (HOMA) | 75 | 0.63 ± 0.47 | 1.68 ± 1.49 | <0.0001 | 0.01 |
| Glucose (mmol/l) | 82 | 4.12 ± 0.55 | 4.33 ± 0.47 | 0.28 | 0.94 |
| Insulin (μU/ml) | 76 | 3.31 ± 2.39 | 8.23 ± 6.37 | <0.0001 | 0.02 |
| Total cholesterol (mg/dl) | 79 | 155.29 ± 26.77 | 168.81 ± 24.29 | <0.05 | 0.76 |
| HDL-cholesterol (mg/dl) | 80 | 50.76 ± 10.41 | 45.35 ± 9.01 | <0.01 | 0.04 |
| LDL-cholesterol (mg/dl) | 80 | 90.14 ± 24.14 | 102.47 ± 18.55 | 0.03 | 0.46 |
| Triglycerides (mg/dl) | 79 | 71.89 ± 42.67 | 98.69 ± 55.18 | <0.01 | 0.41 |
| Systolic BP (mm Hg) | 123 | 107.96 ± 9.95 | 114.17 ± 9.89 | <0.01 | 0.63 |
| Diastolic BP (mm Hg) | 123 | 64.37 ± 5.59 | 65.41 ± 5.82 | 0.44 | 0.68 |
Data presented as mean value ± s.d.
BP, blood pressure; HDL, high-density lipoprotein; HOMA, homeostatic model assessment; IHL, intrahepatic lipid; IMCL, intramyocellular lipid; LDL, low-density lipoprotein; VAT, visceral adipose tissue.
a
Adjusted for race and sex.
b
Adjusted for race, sex, and total body fat.