Table 2. Distribution of Apo-E and ANKK1 gene alleles in percentage.
ApoE | AD (n=50) | NC% (n=56) | ANNK1 | AD% (n=50) | NC% (n=57) |
---|---|---|---|---|---|
2/2,2/3,2/4 | 0/0/0 | 11 (1,6,1)* | TT | 2.0 (1) | 3.5 (2) |
3/3 | 36.0 (18) | 51.8 (29) | CT | 28.0 (14) | 40.4 (23) |
3/4 | 44.0 (22) | 30.4 (17) | CC | 70.0 (35) | 56.1 (32) |
4/4 | 20.0 (10)* | 0.04 (2) |
AD, Alzheimer's Disease, NC, non-cognitive impaired control. There is statistically significant differences in ApoE2 allele (p = 0.003) and ApoE4 (p = 0.03) between AD and NC. There is a trend of higher number of CC (A2/A2) allele in AD than NC (p = 0.33) for ANNK1 gene.