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Cascade of redox reactions leading to bioactivation of the lead benzylMD in Plasmodium-parasitized erythrocytes with formation of different redox-active metabolites and distinct haemoglobin catabolites. The latter are thought to enhance senescence and phagocytosis of pRBC. benzylMD, 3-[substituted-benzyl]-menadiones; pRBC, Plasmodium parasitized red blood cell. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars
