Table 3.
MFI (untreated) | MFI (50 μM NF279a) | Fold-change | |
---|---|---|---|
CD4 | 63.6 | 59.9 | 0.94 |
CXCR4 | 66.0 | 67.7 | 1.03 |
CCR5 | 192.2 | 180.2 | 0.94 |
This high concentration of NF279, which exceeds its fully inhibitory concentration for HXB2pp fusion by ∼5-fold, was selected to better illustrate the lack of effect on CD4 and coreceptor expression.
MFI, mean fluorescence intensity.